Point-of-care and over-the-counter qualitative human chorionic gonadotropin (hCG) devices remain susceptible to false-negative results caused by excess hCG β core fragment.
نویسندگان
چکیده
Employment or Leadership: None declared. Consultant or Advisory Role: None declared. Stock Ownership: None declared. Honoraria: None declared. Research Funding: Bio-Rad Laboratories, ddPCR Reagents, Life Technologies, Acrometrix inhibition panel; K.R. Jerome, Bio-Rad Laboratories. Expert Testimony: None declared. Patents: None declared. Other Remuneration: T.C. Dingle, Bio-Rad Laboratories provided travel and expenses for the Clinical Virology Symposium.
منابع مشابه
Screening method to evaluate point-of-care human chorionic gonadotropin (hCG) devices for susceptibility to the hook effect by hCG β core fragment: evaluation of 11 devices.
BACKGROUND The predominant hCG variant in urine, hCG β core fragment (hCGβcf), has been demonstrated to cause false-negative results in qualitative point-of-care (POC) hCG devices. This is a major concern for healthcare professionals using POC pregnancy tests. We developed a screening method to evaluate qualitative POC hCG devices for their susceptibility to inhibition by hCGβcf. Using this met...
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 59 11 شماره
صفحات -
تاریخ انتشار 2013